The full clinical arc of cardiometabolic care

Resource Hub

A curated destination for teams building GLP-1 and cardiometabolic virtual care programs that extend beyond weight management into diabetes, cardiovascular health, hypertension, metabolic disease, and the indications still to come.

 

80%

of GLP-1 patients present with at least one additional cardiometabolic condition

 

 

1 in 8

US adults are currently on GLP-1 medications, expected to rise to 1 in 5 by end of 2026

 

 

50%+

GLP-1 discontinuation rate at 12 months in programs without dedicated adherence infrastructure

 

- Editor's picks -

The data and thinking shaping the next generation of cardiometabolic virtual care

Start here for the program data, research, and outside perspectives on how GLP-1 and cardiometabolic telehealth programs are being built, scaled, and sustained.

Virtual Care Horizons

Defining growth categories in virtual care

GLP-1 programs now connect hormonal, metabolic, and chronic care across the Wheel platform, driving 70% retention with integrated care versus a 50% industry average.

IQVIA

Thriving in the Complex Landscape of Cardiometabolic Care

Navigating the infrastructure, data, and program design requirements as GLP-1 indications expand across the cardiometabolic market.

Wheel

Millions of Medicare Patients Just Got GLP-1 Coverage. 

With Medicare's GLP-1 Bridge now covering eligible Part D beneficiaries, virtual care programs serving older populations face new infrastructure and eligibility questions.

- Market signals -

Emerging trends shaping cardiometabolic care

Reporting and research on the developments shaping how cardiometabolic telehealth programs are funded, designed, delivered, and measured across weight management, diabetes, cardiovascular care, hypertension, and beyond.

TechTarget

Digital Health Companies Seek Lasting Edge Amid GLP-1 Gold Rush

AJMC

The Expanding Frontier Of Cardiometabolic Care

MedCity News

The New Chronic Condition Care Playbook and How GLP-1s Are Changing the Game

Physicians Weekly

Beyond A1C: How GLP-1 therapy is changing frontline cardiometabolic care

AJMC

Medication Use for Patients With Obesity: Trends and Characteristics for US Employees

JAMA Network Open

GLP-1 Receptor Agonists and Noncardiometabolic Outcomes

- Featured voices -

The people driving cardiometabolic care forward

Interviews and commentary from the clinicians, operators, and policy leaders shaping how cardiometabolic virtual care programs are designed, scaled, and sustained across the full indication arc.

Sean Duffy, CEO and co-founder, Omada Health

Speaking to investors and the press throughout 2025 and 2026, Duffy has argued that the healthcare system is structurally unable to address cardiometabolic disease at scale without a fundamentally different care model. With nearly two-thirds of adults carrying at least one cardiometabolic risk factor, he frames GLP-1s as an entry point into a broader chronic care suite spanning diabetes, hypertension, and obesity, not a standalone solution. His case for between-visit, integrated cardiometabolic care is backed by Omada's own program data.

Kim Boyd, MD, Chief Medical Officer, WeightWatchers

At HLTH Europe 2026, Dr. Boyd argued that GLP-1s will eventually become baseline preventive tools for cardiometabolic health, much like statins. Speaking on a panel examining the gap between clinical innovation and care delivery infrastructure, she noted that while the science of metabolic health has entered a new era, the systems managing it remain archaic. Treating cardiometabolic disease effectively, she said, requires an entirely new model of chronic care, not just a prescription.

- Wheel perspectives -

Original insights from Wheel

Wheel-authored perspectives on building, scaling, and sustaining virtual care programs across weight management, metabolic health, cardiovascular care, and more.

Why GLP-1 Programs Need Virtual Guardrails, AI, and Connected Care to Scale

Virtual guardrails, AI agents, and connected care are shaping the next phase of GLP-1 and cardiometabolic program design. Six insights from an industry roundtable on where virtual care infrastructure needs to go as the indication set expands.

Why Integrated Cardiometabolic Programs Nearly Double Patient Retention

When weight management is paired with integrated multi-condition chronic support, patient retention nearly doubles compared to access-only models. What the data reveals about building programs that sustain engagement over time.

Beyond GLP-1s: Building a Sustainable Virtual Care Model

A look at why sustainable growth in weight management depends on moving beyond prescriptions alone toward integrated, continuous care that supports patients over time.

Build better cardiometabolic experiences with Wheel

Talk with our team about launching or expanding a cardiometabolic telehealth program that improves adherence, extends patient engagement, and scales across indications.

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